Answer
Oestrogen-containing hormonal contraceptives may decrease the efficacy of valproate semisodium (Depakote), so prescribers should monitor clinical response (mood control) when these products are started or stopped.
Sources for this answer
- Depakote 250mg TabletsSANOFI · emc · SmPC §4.4 Special warnings and precautions for use · Version 32Document updated
Sources checked