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Medicines valproate semisodiumQuestion & answer

valproate semisodium · Medicine question

Can valproate semisodium cause severe pancreatitis?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Yes, pancreatitis that may be severe and fatal has been reported very rarely with valproate semisodium (Depakote).

Sources for this answer

Depakote 250mg TabletsSANOFI · emc · SmPC §4.4 Special warnings and precautions for use · Version 32Document updated 2 October 2026

Sources checked 8 November 2026

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valproate semisodium

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How much sodium does each Depakote 250 mg tablet containing valproate semisodium contain?