Answer
Topotecan hydrochloride has been associated with interstitial lung disease, including fatal cases; patients should be monitored for pulmonary symptoms and treatment discontinued if a new diagnosis is confirmed.
Sources for this answer
- Topotecan Hospira 4 mg/4 ml concentrate for solution for infusionPfizer Limited · emc · SmPC §4.4 Special warnings and precautions for use · Version 18Document updated
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