Answer
Topotecan hydrochloride may harm the foetus, having caused embryo-foetal death and malformations in preclinical studies, and patients exposed during pregnancy must be warned of potential foetal hazards.
Sources for this answer
- Topotecan Hospira 4 mg/4 ml concentrate for solution for infusionPfizer Limited · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 18Document updated
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