us guidance

United States clinical guidance

Clinician-facing educational summaries of current US recommendations from national bodies and specialty societies.

cardiovascular prevention

adult hypertension screening and confirmation

A source-separated US summary of adult blood-pressure screening, out-of-office confirmation and classification.

explore adult
diabetes prevention

prediabetes and type 2 diabetes screening and diagnosis

US screening eligibility and diagnostic thresholds for asymptomatic, nonpregnant adults, with USPSTF and ADA recommendations kept separate.

explore prediabetes
bone health

osteoporosis screening to prevent fractures

A bounded summary of the 2025 USPSTF primary-screening recommendations and evidence limits.

explore osteoporosis
cardiovascular

atrial fibrillation

Current US assessment, stroke-prevention, risk-factor, rate-control and rhythm-control priorities for adults with atrial fibrillation.

explore atrial
cardiovascular

chronic heart failure

US staging, phenotype confirmation, guideline-directed therapy, monitoring and referral priorities for adults with chronic heart failure.

explore chronic
cardiovascular

venous thromboembolism (dvt and pulmonary embolism)

Current US diagnosis, severity assessment, anticoagulation, disposition and follow-up priorities for DVT and acute pulmonary embolism.

explore venous
cardiovascular

dyslipidemia and statin-based prevention

The 2026 ACC/AHA US pathway for lipid assessment, PREVENT risk estimation, statin treatment, goals and selective nonstatin intensification.

explore dyslipidemia
cardiovascular

stroke and transient ischemic attack

US emergency recognition and current acute ischemic-stroke and secondary-prevention priorities for stroke and TIA.

explore stroke
cardiovascular

chest pain of recent onset

US recognition, structured risk assessment and evidence-based testing priorities for acute and stable chest pain.

explore chest
cardiovascular

adult valvular heart disease

US evaluation, staging, surveillance and multidisciplinary intervention planning for adult valvular heart disease.

explore adult
cardiovascular

lower-extremity peripheral artery disease

Current US detection, cardiovascular and limb-risk treatment, exercise, foot care and revascularization priorities for lower-extremity PAD.

explore lower-extremity
cardiovascular

familial hypercholesterolemia

US recognition, family assessment, early LDL lowering and specialist escalation for suspected or confirmed familial hypercholesterolemia.

explore familial
cardiovascular

transient loss of consciousness and syncope

US initial assessment, risk stratification and targeted testing for syncope and other transient loss of consciousness.

explore transient
cardiovascular

inclisiran for hypercholesterolemia

US FDA-label and 2026 dyslipidemia-guideline context for selecting, administering and monitoring inclisiran.

explore inclisiran
cardiovascular

abdominal aortic aneurysm

US preventive screening, incidental finding, surveillance and urgent escalation for abdominal aortic aneurysm.

explore abdominal
cardiology

stable angina and chronic coronary disease

US symptom control, event prevention, exercise, testing and revascularization priorities for chronic coronary disease with angina.

explore stable
cardiology

palpitations and suspected supraventricular tachycardia

US rhythm documentation, stability assessment, targeted monitoring and management principles for palpitations and adult SVT.

explore palpitations
cardiology

acute heart failure

US recognition, stabilization, congestion treatment, precipitant assessment and transition priorities for acute heart failure.

explore acute
cardiology / emergency

acute coronary syndromes

Current 2025 US triage, antithrombotic, invasive, revascularization and post-discharge priorities for unstable angina, NSTEMI and STEMI.

explore acute
respiratory

asthma diagnosis and longitudinal care

US-focused asthma confirmation, anti-inflammatory treatment, control review, action planning and exacerbation safety for children and adults.

explore asthma
respiratory

chronic obstructive pulmonary disease

Current COPD confirmation, symptom and exacerbation assessment, inhaled treatment, prevention and acute deterioration priorities for US practice.

explore chronic
respiratory

community-acquired pneumonia in adults

ATS/IDSA-based adult CAP confirmation, site-of-care decisions, microbiology, empiric treatment, stability review and safety escalation.

explore community-acquired
respiratory

obstructive sleep apnea and obesity hypoventilation

AASM and ATS pathways for adult sleep-apnea testing, PAP treatment, obesity-hypoventilation evaluation and urgent respiratory safety.

explore obstructive
respiratory

allergic and nonallergic rhinitis

US allergy-practice guidance for rhinitis classification, targeted testing, intranasal therapy, comorbidity and escalation.

explore allergic
respiratory

chronic cough in adults

CHEST-based classification, red-flag screening, common-cause evaluation, sequential management and referral for cough lasting more than eight weeks.

explore chronic
respiratory

adult non-cystic-fibrosis bronchiectasis

The 2026 CHEST approach to exacerbation antibiotics, airway clearance, suppressive treatment, hemoptysis and selected surgery.

explore adult
renal

chronic kidney disease evaluation and management

KDIGO 2024 confirmation, GFR and albuminuria classification, progression risk, kidney-protective treatment and referral for US care.

explore chronic
renal

acute kidney injury recognition and initial management

KDIGO-based AKI detection, staging, cause evaluation, hemodynamic and medicine review, complication management and escalation.

explore acute
renal

finerenone for ckd associated with type 2 diabetes

US FDA-label and guideline positioning, eligibility checks, potassium monitoring, interactions and cardiorenal follow-up for finerenone.

explore finerenone
renal

acute kidney and ureteral stones: source-status boundary

What the attached AUA directory does and does not establish about the 2026 surgical kidney-stone guideline.

explore acute
renal

kidney-stone metabolic evaluation and recurrence prevention

US stone analysis, risk assessment, urine evaluation, diet, phenotype-directed prevention and longitudinal monitoring after nephrolithiasis.

explore kidney-stone
endocrine & metabolic

established primary hypothyroidism: hormone replacement

A source-bounded ATA hormone-replacement summary for established primary hypothyroidism; diagnostic testing for suspected disease is outside scope.

explore established
endocrine & metabolic

type 1 diabetes in adults

ADA 2026 insulin, glucose technology, education, hypoglycemia, ketosis prevention and complication care for adults with type 1 diabetes.

explore type
endocrine & metabolic

diabetes-related foot prevention and urgent problems

ADA 2026 foot-risk examination, patient education, ulcer, infection, ischemia and Charcot escalation for US care.

explore diabetes-related
endocrine & metabolic

primary adrenal insufficiency and adrenal crisis

Endocrine Society diagnosis, replacement, sick-day preparation and emergency treatment for primary adrenal insufficiency.

explore primary
endocrine & metabolic

adult hyponatremia: diagnosis and safe correction

A cautious US-oriented approach to tonicity, symptom and duration assessment, etiologic testing, monitored treatment and overcorrection prevention.

explore adult
endocrine & metabolic

primary hyperparathyroidism

Fifth International Workshop confirmation, target-organ evaluation, surgery selection, monitoring and hypercalcemia safety.

explore primary
endocrine & metabolic

vitamin d testing, prevention and established indications

A scope-safe reading of the 2024 Endocrine Society guideline, separating population prevention from diagnosis and treatment of established vitamin D disorders.

explore vitamin
dermatology

acne vulgaris assessment and management

AAD-based acne severity assessment, combination topical treatment, antibiotic stewardship, isotretinoin referral and scar prevention for US practice.

explore acne
dermatology

atopic dermatitis across the lifespan

Current AAD topical, systemic and pediatric principles for diagnosing atopic dermatitis, restoring the skin barrier, controlling inflammation and escalating safely.

explore atopic
dermatology

psoriasis assessment and treatment selection

AAD–NPF assessment of cutaneous psoriasis, high-impact sites, psoriatic arthritis, comorbidity, topical care and specialist escalation in US practice.

explore psoriasis
dermatology

scabies recognition, treatment and contact control

CDC-based classic and crusted scabies treatment, simultaneous contact management, environmental measures and post-treatment review.

explore scabies
dermatology

tinea corporis, cruris and pedis

CDC-based diagnosis, topical treatment, steroid avoidance, resistant dermatophyte recognition and escalation for common cutaneous tinea.

explore tinea
dermatology

phenotype-led rosacea care

National Rosacea Society consensus for diagnosing rosacea by phenotype, selecting feature-specific treatment and recognizing ocular disease.

explore phenotype-led
dermatology

alopecia areata recognition and treatment planning

US diagnosis, severity documentation, limited-disease options, referral and current FDA-labeled systemic treatment context for alopecia areata.

explore alopecia
dermatology

baricitinib for severe alopecia areata

FDA-labeled adult severe-alopecia use of baricitinib, with pretreatment evaluation, risk selection, monitoring and the June 2026 hypoglycemia warning.

explore baricitinib
dermatology

ritlecitinib for severe alopecia areata

June 2026 FDA-labeled use of ritlecitinib for adults and adolescents aged 12 years or older, including baseline testing and JAK-class safety.

explore ritlecitinib
metabolic

adult overweight and obesity management

US intensive behavioral treatment and obesity pharmacotherapy, with metabolic-surgery eligibility retained as an explicit evidence gap.

explore adult
endocrinology / obesity

semaglutide (wegovy) for chronic weight management

Current US Wegovy indications, formulation-specific initiation, monitoring, contraindications and long-term treatment review.

explore semaglutide
endocrinology / obesity

tirzepatide (zepbound) for chronic weight management

Current US Zepbound eligibility, dose escalation, monitoring, interactions, reproductive counseling and serious adverse-effect boundaries.

explore tirzepatide
cardiovascular & renal

dapagliflozin (farxiga) for chronic kidney disease

FDA-label and KDIGO positioning, renal-function and volume checks, ketoacidosis prevention, infection safety and peri-procedural planning.

explore dapagliflozin
cardiovascular & renal

empagliflozin (jardiance) for chronic kidney disease

FDA-label and KDIGO positioning, kidney and volume assessment, ketoacidosis and infection safety, and coordinated CKD follow-up.

explore empagliflozin
urgent care

nosebleed assessment and control

AAO-HNSF first aid, focused examination, packing and cautery principles, antithrombotic safety and referral for epistaxis in patients aged three years or older.

explore nosebleed
urgent care

acute red eye triage in ambulatory care

AAO-based differentiation of uncomplicated conjunctivitis from keratitis and other sight-threatening red-eye presentations, with contact-lens and referral safety.

explore acute
infection & public health

measles recognition, isolation and public-health response

CDC 2026 recognition, immediate airborne precautions, paired PCR and serology, mandatory reporting, supportive care and exposure coordination.

explore measles
infection & public health

child and adolescent immunization review

A safe workflow for applying the current CDC/ACIP age, catch-up, medical-indication and special-situation schedules without freezing a changing vaccine table.

explore child
infection & public health

adult immunization review

CDC/ACIP age-based, risk-based, pregnancy, catch-up and shared-decision vaccination workflow for US adults.

explore adult
sexual health

syphilis diagnosis, staging and treatment

CDC stage-specific serology, penicillin treatment, pregnancy, neurologic and ocular escalation, partner services and response monitoring.

explore syphilis
sexual health

gonorrhea testing, treatment and resistance response

CDC anatomic-site testing, weight-based ceftriaxone treatment, chlamydia coverage, pharyngeal test of cure, partner care and suspected resistance escalation.

explore gonorrhea
public health

hiv preexposure prophylaxis

CDC HIV PrEP eligibility, baseline exclusion of acute HIV, oral and injectable choices, kidney and hepatitis B safety and continuing monitoring.

explore hiv
infection

hiv nonoccupational postexposure prophylaxis

CDC 2025 emergency nPEP evaluation, prompt three-drug initiation, 28-day completion, exposure-source testing and transition to PrEP.

explore hiv
infection

urinary tract infection assessment and stewardship

US-focused differentiation of bladder-limited and systemic urinary infection, selective testing, empiric treatment review and safety escalation.

explore urinary
infections

lower urinary tract infection in women

A US pathway for acute cystitis in nonpregnant and pregnant patients, with explicit boundaries for pyelonephritis and asymptomatic bacteriuria.

explore lower
infection

acute sore throat and streptococcal pharyngitis

US risk assessment, selective group A streptococcal testing, antibiotic stewardship and deep-neck-infection safety for children and adults.

explore acute
infection

acute otitis media in children

US pediatric diagnostic criteria, pain treatment, observation options, antimicrobial stewardship and complication escalation.

explore acute
infection

adult rhinosinusitis

US differentiation of viral and bacterial acute rhinosinusitis, shared treatment decisions, chronic-disease confirmation and safety referral.

explore adult
infection

lyme disease prevention, diagnosis and treatment

North American tick-bite risk assessment, erythema migrans diagnosis, staged testing, treatment boundaries and organ-specific escalation.

explore lyme
infection

acute cough and uncomplicated bronchitis stewardship

US assessment of acute cough, exclusion of pneumonia, antibiotic avoidance and return precautions for uncomplicated bronchitis.

explore acute
infection

impetigo and ecthyma

US diagnosis, limited-versus-extensive treatment, culture strategy, transmission control and deeper-infection escalation.

explore impetigo
infections

cellulitis and erysipelas

US distinction of nonpurulent cellulitis from abscess, severity assessment, focused microbiology and necrotizing-infection escalation.

explore cellulitis
infection

acute diffuse otitis externa

US diagnosis, pain control, topical first-line therapy, drop-delivery optimization and malignant-otitis-externa escalation.

explore acute
infection

long covid clinical assessment and support

CDC-aligned patient-centered evaluation, symptom-directed care, post-exertional-malaise safety and functional support for Long COVID.

explore long
infection

herpes zoster recognition and early treatment

US diagnosis, timely antiviral treatment, ophthalmic and disseminated-disease escalation, transmission precautions and prevention follow-up.

explore herpes
infection

infectious conjunctivitis in adults and children

AAO-aligned differentiation of viral, bacterial and high-risk conjunctivitis, antibiotic stewardship and urgent corneal referral.

explore infectious
infection

nirmatrelvir–ritonavir for outpatient covid-19

US FDA-label and CDC workflow for time-critical Paxlovid eligibility, interaction reconciliation, organ-function dosing and safety follow-up.

explore nirmatrelvir–ritonavir
infection

genital herpes diagnosis, treatment and counseling

CDC-aligned lesion testing, first-episode and recurrent treatment decisions, transmission counseling and pregnancy safety.

explore genital
infection

hepatitis b screening and test interpretation

CDC universal adult triple-panel screening, pregnancy and risk-based testing, result interpretation and linkage to liver care.

explore hepatitis
infection

hepatitis c screening, confirmation and linkage

CDC universal adult and pregnancy screening, antibody-to-RNA confirmation, reinfection testing and linkage to curative treatment.

explore hepatitis
infection

hiv screening and diagnostic testing in primary care

USPSTF universal screening, pregnancy testing, repeat risk-based testing, acute-HIV recognition and rapid linkage to care.

explore hiv
infection

pertussis recognition, treatment and public-health response

CDC-aligned clinical recognition, nasopharyngeal testing, early treatment, post-exposure prophylaxis and infant-risk escalation.

explore pertussis
infection

pinworm infection diagnosis and household control

CDC-based tape testing, two-dose treatment logic, household hygiene and special-population precautions for Enterobius vermicularis.

explore pinworm
digestive

dyspepsia and gastroesophageal reflux disease

US evaluation and treatment of uninvestigated dyspepsia and GERD, including endoscopy triggers, H. pylori testing, proton-pump-inhibitor use and objective testing.

explore dyspepsia
digestive

metabolic dysfunction-associated steatotic liver disease

Current US MASLD recognition, noninvasive fibrosis risk stratification, metabolic treatment, referral and cirrhosis surveillance.

explore metabolic
digestive

irritable bowel syndrome in adults

ACG-based positive diagnosis, focused exclusion testing, diet, subtype-directed treatment and gut–brain behavioral care for IBS.

explore irritable
digestive

celiac disease

ACG-based case finding, serology and biopsy diagnosis, gluten-free treatment, nutritional assessment and follow-up for celiac disease.

explore celiac
digestive

pharmacologic treatment of chronic idiopathic constipation

The 2023 AGA/ACG medicine recommendations for adults already diagnosed with chronic idiopathic constipation.

explore pharmacologic
digestive

hemorrhoidal disease

ASCRS-based evaluation, bowel-habit treatment, office procedures, surgery selection and rectal-bleeding safety for symptomatic hemorrhoids.

explore hemorrhoidal
digestive

anal fissure in adults

ASCRS-based recognition and staged care of acute and chronic anal fissure, including conservative care, topical therapy, botulinum toxin and surgery.

explore anal
digestive

colonic diverticulitis

The 2026 ACG approach to diagnosis, selective outpatient care and antibiotics, recurrence prevention, colon evaluation and individualized surgery.

explore colonic
digestive

suspected inflammatory bowel disease in adults

Current US recognition and diagnostic confirmation of ulcerative colitis and Crohn disease, including infection exclusion, endoscopy, imaging and urgent escalation.

explore suspected
digestive

evaluation of abnormal liver chemistries

ACG-based confirmation, injury-pattern classification, etiologic evaluation and urgency assessment for abnormal aminotransferases, alkaline phosphatase or bilirubin.

explore evaluation
digestive

right-upper-quadrant pain and suspected bile-duct stones

A bounded US summary of ACR biliary imaging and ASGE choledocholithiasis risk stratification; operative and antimicrobial management remain outside this source set.

explore right-upper-quadrant
digestive

acute pancreatitis

The 2024 ACG pathway for diagnosis, early severity assessment, fluids, feeding, biliary intervention and pancreatic-necrosis management.

explore acute
digestive

acute infectious diarrhea in adults

IDSA-based assessment, rehydration, selective stool testing and antibiotic stewardship for acute diarrhea in US and travel settings.

explore acute
digestive

acute upper gastrointestinal bleeding

ACG-based emergency risk assessment, resuscitation, transfusion, endoscopy, hemostasis and post-endoscopic care for overt upper GI bleeding.

explore acute
musculoskeletal

hand, hip and knee osteoarthritis

ACR/Arthritis Foundation–based nonoperative management for hand, hip and knee osteoarthritis; arthroplasty timing remains an evidence gap.

explore hand,
musculoskeletal

low back pain with or without radicular symptoms

VA/DoD-based triage, selective imaging, active rehabilitation, medication stewardship and escalation for acute and chronic low back pain.

explore low
musculoskeletal

established rheumatoid arthritis: pharmacologic treatment

ACR-based treatment of established rheumatoid arthritis; recognition, diagnostic testing and referral remain an explicit source gap.

explore established
musculoskeletal

polymyalgia rheumatica

Recognition, exclusion of mimics, glucocorticoid treatment, relapse monitoring and giant-cell-arteritis safety in polymyalgia rheumatica.

explore polymyalgia
musculoskeletal

giant cell arteritis

ACR/Vasculitis Foundation–based emergency recognition, diagnostic confirmation, vascular imaging and glucocorticoid-sparing care for GCA.

explore giant
musculoskeletal

established axial spondyloarthritis: treatment

The 2026 ACR treatment update for established axial spondyloarthritis; diagnosis and sacroiliac imaging remain an explicit source gap.

explore established
musculoskeletal

adult rotator cuff injury

AAOS 2025 evaluation, rehabilitation, injection, imaging and operative decision-making for adult rotator cuff tears.

explore adult
musculoskeletal

carpal tunnel syndrome

AAOS 2024 diagnosis, selective electrodiagnostic testing, splint and injection options, surgical release and postoperative care.

explore carpal
msk

gout flares and urate-lowering therapy

ACR-based diagnosis, acute flare treatment, allopurinol-first treat-to-target therapy, prophylaxis and comorbidity-aware care.

explore gout
neurology

headache assessment and primary-headache classification

US-focused secondary-headache triage, phenotype diagnosis, selective testing, medication-overuse prevention and follow-up.

explore headache
neurology

migraine acute treatment and prevention

US individualized acute and preventive migraine care, medication-overuse control, reproductive safety and escalation.

explore migraine
neurology

adult first unprovoked seizure: prognosis and treatment decision

AAN/AES evidence on recurrence prognosis and whether to start immediate treatment after an adult first unprovoked seizure.

explore adult
neurology

benign paroxysmal positional vertigo

US bedside diagnosis, canalith repositioning, low-value-test avoidance, fall-risk assessment and central-vertigo escalation.

explore benign
neurology

bell's palsy recognition and early care

US exclusion of stroke and structural causes, time-sensitive corticosteroid treatment, corneal protection and follow-up.

explore bell's
neurology

adult age-related hearing loss identification and care

US screening, otoscopy, audiologic confirmation, communication support, amplification and urgent asymmetric-loss referral.

explore adult
neurology

tinnitus assessment and quality-of-life management

US red-flag assessment, audiology, education, sound strategies, cognitive behavioral care and low-value-treatment avoidance.

explore tinnitus
neurology

trigeminal neuralgia recognition and specialist treatment

US phenotype recognition, structural-cause evaluation, medication safety and neurosurgical referral for trigeminal neuralgia.

explore trigeminal
neurology

cognitive decline and dementia diagnostic evaluation

US patient-centered recognition, tiered evaluation, collateral history, diagnosis disclosure and early care planning for suspected dementia.

explore cognitive
neurology

parkinson disease diagnosis and early motor treatment

US recognition, movement-specialist confirmation, initial dopaminergic treatment and adverse-effect monitoring for early Parkinson disease.

explore parkinson
neurology

multiple sclerosis diagnosis and disease-modifying care

US application of the 2024 McDonald criteria, specialist confirmation, individualized disease-modifying therapy and longitudinal safety monitoring.

explore multiple
neurology

distal symmetric polyneuropathy evaluation

A source-bounded AAN summary of laboratory and genetic testing in distal symmetric polyneuropathy; broader management remains blocked.

explore distal
neurology

amyotrophic lateral sclerosis recognition and multidisciplinary care

US urgent recognition, specialist diagnosis, respiratory and nutrition surveillance, multidisciplinary care and preference-sensitive planning for ALS.

explore amyotrophic
mental health & neurodevelopmental

pediatric adhd diagnosis and longitudinal treatment

AAP-aligned multi-setting evaluation, comorbidity assessment, age-specific behavioral and medication treatment, school support and monitoring.

explore pediatric
mental health & neurodevelopmental

adult autism: federal source-scope boundary

What the attached CDC diagnostic page and HHS lifespan-services research plan do and do not establish for adult autism care.

explore adult
mens health

lower urinary tract symptoms attributed to benign prostatic hyperplasia

AUA-based evaluation and shared medical or procedural management of bothersome LUTS attributed to benign prostatic hyperplasia.

explore lower
mens health

male lower urinary tract symptoms: differential and initial pathway

A symptom-led US approach separating bladder storage, outlet obstruction, infection, neurologic dysfunction and retention before treatment.

explore male
mens health

erectile dysfunction

AUA-based evaluation of erectile dysfunction as a sexual-health and cardiovascular-risk marker, with staged shared treatment.

explore erectile
mens health

acute epididymitis and epididymo-orchitis

CDC-based torsion exclusion, STI and urinary testing, organism-directed empiric therapy, partner care and follow-up.

explore acute
mens health

acute nontraumatic scrotal pain: imaging evidence boundary

ACR imaging appropriateness for acute scrotal pain, with operative torsion management kept outside the attached source scope.

explore acute
women's health

menopause symptom assessment and treatment

The Menopause Society approach to individualized hormone and evidence-based nonhormone treatment for bothersome menopausal symptoms.

explore menopause
women's health

heavy menstrual bleeding and abnormal uterine bleeding

ACOG-based diagnosis and acute abnormal-uterine-bleeding management; chronic stable treatment remains an explicit source gap.

explore heavy
women's health

suspected endometriosis: diagnosis and initial pathway

ACOG 2026 diagnostic guidance for clinical recognition, imaging, presumptive diagnosis and timely shared decisions without mandatory diagnostic surgery.

explore suspected
women's health

hypertensive disorders of pregnancy

ACOG differentiation of chronic and gestational hypertension, preeclampsia surveillance, severe-feature escalation and CHAP-informed treatment.

explore hypertensive
women's health

diabetes before, during and after pregnancy

ADA 2026 preconception optimization, pregnancy glucose monitoring, insulin-first pharmacotherapy, technology and postpartum follow-up.

explore diabetes
women's health

urinary incontinence and pelvic organ prolapse

ACOG/AUGS symptom-led evaluation, conservative care and referral boundaries for urinary leakage and pelvic organ prolapse.

explore urinary
women's health

bacterial vaginosis

CDC diagnosis and treatment of symptomatic bacterial vaginosis with the 2025 ACOG recurrent-BV partner-therapy update.

explore bacterial
women's health

vulvovaginal candidiasis

CDC differentiation of uncomplicated, recurrent, severe and non-albicans vulvovaginal candidiasis with pregnancy and resistance boundaries.

explore vulvovaginal
women's health

pelvic inflammatory disease

CDC low-threshold diagnosis, empiric broad treatment, hospitalization criteria, partner care and 72-hour response review for acute PID.

explore pelvic
women's health

uncomplicated chlamydial infection

CDC testing, site-specific treatment, pregnancy follow-up, partner management and repeat testing for uncomplicated chlamydial infection.

explore uncomplicated
women's health

emergency contraception

CDC U.S. SPR timing, method selection, post-ulipristal contraception and follow-up after emergency contraception.

explore emergency
women's health

ectopic pregnancy and early pregnancy loss

ACOG evaluation of pregnancy of unknown location, ectopic-pregnancy urgency and patient-centered management of confirmed early pregnancy loss.

explore ectopic
women's health

combined hormonal contraception

CDC eligibility screening, person-centered initiation, backup and safety follow-up for pills, patches and vaginal rings.

explore combined
women's health

progestin-only pills

CDC method-specific eligibility, initiation, missed-pill instructions and follow-up for US progestin-only oral contraception.

explore progestin-only
women's health

long-acting reversible contraception

CDC person-centered initiation and follow-up for intrauterine devices, contraceptive implants and injectable contraception.

explore long-acting
women's health

polycystic ovary syndrome

2023 international PCOS diagnostic criteria, life-course risk assessment and goal-directed reproductive, metabolic and symptom management.

explore polycystic
women's health

prepregnancy counseling

ACOG and ASRM preparation for pregnancy through reproductive goals, condition and medication optimization, prevention and equitable risk review.

explore prepregnancy
women's health

recurrent pregnancy loss

ASRM 2026 definition, evidence-based staged evaluation, cause-directed treatment and prognosis after recurrent pregnancy loss.

explore recurrent
cancer & referral

possible cancer in primary care: symptom-led evaluation

A US symptom-led safety framework for investigating possible cancer without imposing one universal referral clock across organ systems.

explore possible
cancer & referral

elevated psa and suspected prostate cancer

AUA/SUO 2026 shared decision, repeat-PSA and risk-adapted urology pathway for possible clinically significant prostate cancer.

explore elevated
cancer & referral

gross and microscopic hematuria

AUA/SUFU 2025 confirmation, risk stratification, cystoscopy and upper-tract evaluation for adult hematuria.

explore gross
cancer & referral

palpable breast mass: initial imaging and referral

Age- and context-matched ACR imaging, clinical–radiologic concordance and tissue diagnosis for a new palpable breast finding.

explore palpable
cancer & referral

rectal bleeding and iron-deficiency anemia evaluation

A source-bounded US summary of iron-deficiency-anemia evaluation and rectal bleeding when hemorrhoids are suspected; broader cancer symptoms remain blocked.

explore rectal
cancer & referral

suspicious skin lesions: recognition, biopsy and referral

Symptom-led recognition and tissue diagnosis of melanoma and keratinocyte cancer, distinct from population screening.

explore suspicious
cancer & referral

possible ovarian cancer and adnexal mass

US ovarian-screening limits and ACR adnexal-mass imaging; oncology referral and procedural planning remain explicit evidence gaps.

explore possible
cancer & referral

metastatic epidural spinal cord or cauda-equina compression

Emergency recognition, MRI, corticosteroid and multidisciplinary surgical–radiation management of malignant neural compression.

explore metastatic
mental health

major depressive disorder assessment and treatment

VA/DoD-aligned adult depression assessment, shared treatment selection, measurement-based follow-up and urgent risk escalation.

explore major
mental health

adult anxiety-disorder screening

USPSTF preventive-screening guidance for anxiety disorders in asymptomatic adults, including age limits and the required diagnostic follow-through.

explore adult
mental health

me/cfs recognition and symptom-prioritized care

CDC-bounded recognition of post-exertional malaise, exclusion of alternatives, energy management and support for severe disease.

explore me/cfs
mental health

chronic insomnia disorder assessment and treatment

VA/DoD-aligned clinical diagnosis, CBT-I first-line care, selective sleep testing and medication safety review.

explore chronic
mental health

daridorexant for adult insomnia

US FDA-label boundaries for daridorexant placed within CBT-I-first chronic-insomnia assessment and follow-up.

explore daridorexant
mental health / addiction

alcohol misuse and alcohol use disorder

VA/DoD-aligned screening, diagnostic assessment, withdrawal triage, evidence-based treatment and longitudinal harm reduction.

explore alcohol
mental health

bipolar disorder diagnosis and episode management

VA/DoD-aligned diagnostic triage, phase-specific treatment, maintenance planning and high-risk escalation for adult bipolar disorder.

explore bipolar
mental health

first-episode psychosis and schizophrenia care

VA/DoD-aligned early recognition, medical and substance differential, coordinated specialty care and antipsychotic safety monitoring.

explore first-episode
mental health

eating-disorder assessment and treatment planning

APA-aligned comprehensive assessment, medical-stability triage, diagnosis-specific psychotherapy and coordinated nutrition rehabilitation.

explore eating-disorder
mental health

suicide-related self-harm assessment and safety planning

VA/DoD-aligned identification, comprehensive suicide-risk assessment, collaborative safety planning and risk-tailored disposition.

explore suicide-related
mental health

ptsd assessment and evidence-based treatment

VA/DoD-aligned diagnostic assessment, trauma-focused psychotherapy, selected pharmacotherapy and comorbidity-aware follow-up.

explore ptsd
mental health

perinatal mental-health screening and treatment

ACOG-aligned universal screening with care systems, bipolar assessment, individualized treatment and emergency postpartum escalation.

explore perinatal
acute medicine / older people

delirium: recognition, cause-finding and safer management

A deliberately bounded AGS postoperative and SCCM ICU delirium summary with multicomponent care and source-specific medication limits.

explore delirium:
acute medicine / older people

iron-deficiency anemia: confirmation, cause and replacement

AGA-based confirmation, bleeding and malabsorption investigation, oral or intravenous iron and response monitoring.

explore iron-deficiency
acute medicine / older people

falls assessment and prevention in older adults

USPSTF and CDC STEADI risk identification, injury assessment, exercise and individualized multifactorial intervention.

explore falls
acute medicine / older people

older adults with multimorbidity: priorities and coordinated decisions

AGS priority-, trajectory- and burden-aware decisions when multiple disease guidelines and treatments conflict.

explore older
hematology

vitamin b12 and folate deficiency anemia

NIH biochemical evidence and current US label safety for assessment and replacement of vitamin B12 and folate deficiency.

explore vitamin
vascular / dermatology

symptomatic lower-extremity varicose veins

North American multisociety evaluation, duplex confirmation, conservative options and preference-sensitive superficial venous intervention.

explore symptomatic
vascular / dermatology

chronic leg-ulcer infection: source boundary

A transparent account of why the attached US society records do not establish a current chronic leg-ulcer infection pathway.

explore chronic
vascular / dermatology

raynaud's phenomenon recognition and triage

ACR educational recognition material for Raynaud phenomenon, with testing and medication selection kept outside the source scope.

explore raynaud's
vascular / dermatology

venous leg-ulcer management: archived-source boundary

A source-status summary explaining why the attached society records do not support a current active venous-leg-ulcer management pathway.

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pain

chronic noncancer pain assessment and safer treatment

US person-centered chronic-pain evaluation, multimodal nonopioid care and flexible CDC/VA-DoD opioid safety principles.

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pain

painful diabetic polyneuropathy treatment

AAN guidance on oral, topical and nonpharmacologic treatment options for adults with established painful diabetic polyneuropathy.

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palliative care

palliative care and end-of-life planning

US serious-illness palliative assessment, symptom and caregiver support, advance-care planning and clear separation from the Medicare hospice benefit.

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emergency / allergy

anaphylaxis recognition, emergency treatment and follow-up

JTFPP-based immediate epinephrine treatment, physiologic support, observation decisions and prevention after anaphylaxis.

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emergency / allergy

urticaria and angioedema outside anaphylaxis

Acute urticaria phenotype, important mimics and emergency safety boundaries, with chronic drug sequencing kept outside scope.

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emergency / allergy

head injury assessment and early management

Age-appropriate emergency assessment, selective imaging, safe discharge and graded recovery using current ACEP and CDC sources.

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public health / prevention

tobacco smoking dependence assessment and treatment

USPSTF and ATS-informed behavioral support, pharmacotherapy and longitudinal relapse care with pregnancy and vaping evidence boundaries.

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public health / prevention

medication reconciliation and safer transitions

AHRQ-based medication-history verification, discrepancy resolution, transition communication and federal adverse-event reporting.

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safeguarding

recognition and evaluation of suspected child physical abuse

AAP-based recognition, trauma-informed examination and documentation, protective reporting and state-law boundaries.

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infection & safety

suspected sepsis and septic shock

Current adult and pediatric Surviving Sepsis Campaign priorities for immediate recognition, resuscitation, antimicrobials, source control, reassessment and US hospital implementation.

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infection & safety

fever in children younger than 5 years

Age-stratified US assessment of a febrile young child, with separate pathways for young infants, source-directed evaluation, sepsis screening and safe disposition.

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infection & safety

meningococcal disease: cdc clinical guidance

Current CDC recognition, diagnostic testing, empiric treatment and carriage-eradication guidance for suspected meningococcal disease.

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pediatrics

bronchiolitis in infants and young children

Clinical diagnosis and supportive management of uncomplicated bronchiolitis, with explicit exclusion criteria and escalation for respiratory failure, apnea or dehydration.

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pediatrics

acute gastroenteritis and dehydration in children younger than 5 years

Hydration-first management with source-directed stool testing, early nutrition, antimicrobial stewardship and escalation for shock or a surgical presentation.

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pediatrics

viral croup: assessment and management

Severity-based management of barking cough and stridor with minimal agitation, corticosteroid treatment, nebulized epinephrine when indicated and airway escalation.

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pediatrics

urinary tract infection in children and adolescents

Probability-based urine testing, uncontaminated collection, urinalysis-plus-culture diagnosis, local antimicrobial selection, result follow-up and selective imaging.

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pediatrics

functional constipation in children and adolescents

Current AGA–NASPGHAN assessment and stepwise care emphasizing clinical diagnosis, alarm features, disimpaction, maintenance, behavioral support and escalation.

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pediatrics

neonatal hyperbilirubinemia in infants born at 35 weeks or later

AAP 2022 bilirubin measurement, hour-specific risk assessment, feeding support, follow-up and urgent escalation for infants born at 35 weeks or later.

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pediatrics

febrile seizures in young children

Classification, emergency seizure care, fever-source assessment, restraint in testing after a simple event and escalation after complex or atypical seizures.

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