us directory

United States guidance directory

Search source-attributed educational summaries available for this region.

190 pages

Cardiovascular prevention

Adult hypertension screening and confirmation

A source-separated US summary of adult blood-pressure screening, out-of-office confirmation and classification.

reviewed 2026-08-20
Diabetes prevention

Prediabetes and type 2 diabetes screening and diagnosis

US screening eligibility and diagnostic thresholds for asymptomatic, nonpregnant adults, with USPSTF and ADA recommendations kept separate.

reviewed 2026-08-20
Bone health

Osteoporosis screening to prevent fractures

A bounded summary of the 2025 USPSTF primary-screening recommendations and evidence limits.

reviewed 2026-08-20
Cardiovascular

Atrial fibrillation

Current US assessment, stroke-prevention, risk-factor, rate-control and rhythm-control priorities for adults with atrial fibrillation.

reviewed 2026-08-20
Cardiovascular

Chronic heart failure

US staging, phenotype confirmation, guideline-directed therapy, monitoring and referral priorities for adults with chronic heart failure.

reviewed 2026-08-20
Cardiovascular

Venous thromboembolism (DVT and pulmonary embolism)

Current US diagnosis, severity assessment, anticoagulation, disposition and follow-up priorities for DVT and acute pulmonary embolism.

reviewed 2026-08-20
Cardiovascular

Dyslipidemia and statin-based prevention

The 2026 ACC/AHA US pathway for lipid assessment, PREVENT risk estimation, statin treatment, goals and selective nonstatin intensification.

reviewed 2026-08-20
Cardiovascular

Stroke and transient ischemic attack

US emergency recognition and current acute ischemic-stroke and secondary-prevention priorities for stroke and TIA.

reviewed 2026-08-20
Cardiovascular

Chest pain of recent onset

US recognition, structured risk assessment and evidence-based testing priorities for acute and stable chest pain.

reviewed 2026-08-20
Cardiovascular

Adult valvular heart disease

US evaluation, staging, surveillance and multidisciplinary intervention planning for adult valvular heart disease.

reviewed 2026-08-20
Cardiovascular

Lower-extremity peripheral artery disease

Current US detection, cardiovascular and limb-risk treatment, exercise, foot care and revascularization priorities for lower-extremity PAD.

reviewed 2026-08-20
Cardiovascular

Familial hypercholesterolemia

US recognition, family assessment, early LDL lowering and specialist escalation for suspected or confirmed familial hypercholesterolemia.

reviewed 2026-08-20
Cardiovascular

Transient loss of consciousness and syncope

US initial assessment, risk stratification and targeted testing for syncope and other transient loss of consciousness.

reviewed 2026-08-20
Cardiovascular

Inclisiran for hypercholesterolemia

US FDA-label and 2026 dyslipidemia-guideline context for selecting, administering and monitoring inclisiran.

reviewed 2026-08-20
Cardiovascular

Abdominal aortic aneurysm

US preventive screening, incidental finding, surveillance and urgent escalation for abdominal aortic aneurysm.

reviewed 2026-08-20
Cardiology

Stable angina and chronic coronary disease

US symptom control, event prevention, exercise, testing and revascularization priorities for chronic coronary disease with angina.

reviewed 2026-08-20
Cardiology

Palpitations and suspected supraventricular tachycardia

US rhythm documentation, stability assessment, targeted monitoring and management principles for palpitations and adult SVT.

reviewed 2026-08-20
Cardiology

Acute heart failure

US recognition, stabilization, congestion treatment, precipitant assessment and transition priorities for acute heart failure.

reviewed 2026-08-20
Cardiology / Emergency

Acute coronary syndromes

Current 2025 US triage, antithrombotic, invasive, revascularization and post-discharge priorities for unstable angina, NSTEMI and STEMI.

reviewed 2026-08-20
Respiratory

Asthma diagnosis and longitudinal care

US-focused asthma confirmation, anti-inflammatory treatment, control review, action planning and exacerbation safety for children and adults.

reviewed 2026-08-20
Respiratory

Chronic obstructive pulmonary disease

Current COPD confirmation, symptom and exacerbation assessment, inhaled treatment, prevention and acute deterioration priorities for US practice.

reviewed 2026-08-20
Respiratory

Community-acquired pneumonia in adults

ATS/IDSA-based adult CAP confirmation, site-of-care decisions, microbiology, empiric treatment, stability review and safety escalation.

reviewed 2026-08-20
Respiratory

Obstructive sleep apnea and obesity hypoventilation

AASM and ATS pathways for adult sleep-apnea testing, PAP treatment, obesity-hypoventilation evaluation and urgent respiratory safety.

reviewed 2026-08-20
Respiratory

Allergic and nonallergic rhinitis

US allergy-practice guidance for rhinitis classification, targeted testing, intranasal therapy, comorbidity and escalation.

reviewed 2026-08-20
Respiratory

Chronic cough in adults

CHEST-based classification, red-flag screening, common-cause evaluation, sequential management and referral for cough lasting more than eight weeks.

reviewed 2026-08-20
Respiratory

Adult non-cystic-fibrosis bronchiectasis

The 2026 CHEST approach to exacerbation antibiotics, airway clearance, suppressive treatment, hemoptysis and selected surgery.

reviewed 2026-08-20
Renal

Chronic kidney disease evaluation and management

KDIGO 2024 confirmation, GFR and albuminuria classification, progression risk, kidney-protective treatment and referral for US care.

reviewed 2026-08-20
Renal

Acute kidney injury recognition and initial management

KDIGO-based AKI detection, staging, cause evaluation, hemodynamic and medicine review, complication management and escalation.

reviewed 2026-08-20
Renal

Finerenone for CKD associated with type 2 diabetes

US FDA-label and guideline positioning, eligibility checks, potassium monitoring, interactions and cardiorenal follow-up for finerenone.

reviewed 2026-08-20
Renal

Acute kidney and ureteral stones: source-status boundary

What the attached AUA directory does and does not establish about the 2026 surgical kidney-stone guideline.

reviewed 2026-08-20
Renal

Kidney-stone metabolic evaluation and recurrence prevention

US stone analysis, risk assessment, urine evaluation, diet, phenotype-directed prevention and longitudinal monitoring after nephrolithiasis.

reviewed 2026-08-20
Endocrine & metabolic

Established primary hypothyroidism: hormone replacement

A source-bounded ATA hormone-replacement summary for established primary hypothyroidism; diagnostic testing for suspected disease is outside scope.

reviewed 2026-08-20
Endocrine & metabolic

Type 1 diabetes in adults

ADA 2026 insulin, glucose technology, education, hypoglycemia, ketosis prevention and complication care for adults with type 1 diabetes.

reviewed 2026-08-20
Endocrine & metabolic

Diabetes-related foot prevention and urgent problems

ADA 2026 foot-risk examination, patient education, ulcer, infection, ischemia and Charcot escalation for US care.

reviewed 2026-08-20
Endocrine & metabolic

Primary adrenal insufficiency and adrenal crisis

Endocrine Society diagnosis, replacement, sick-day preparation and emergency treatment for primary adrenal insufficiency.

reviewed 2026-08-20
Endocrine & metabolic

Adult hyponatremia: diagnosis and safe correction

A cautious US-oriented approach to tonicity, symptom and duration assessment, etiologic testing, monitored treatment and overcorrection prevention.

reviewed 2026-08-20
Endocrine & metabolic

Primary hyperparathyroidism

Fifth International Workshop confirmation, target-organ evaluation, surgery selection, monitoring and hypercalcemia safety.

reviewed 2026-08-20
Endocrine & metabolic

Vitamin D testing, prevention and established indications

A scope-safe reading of the 2024 Endocrine Society guideline, separating population prevention from diagnosis and treatment of established vitamin D disorders.

reviewed 2026-08-20
Dermatology

Acne vulgaris assessment and management

AAD-based acne severity assessment, combination topical treatment, antibiotic stewardship, isotretinoin referral and scar prevention for US practice.

reviewed 2026-08-20
Dermatology

Atopic dermatitis across the lifespan

Current AAD topical, systemic and pediatric principles for diagnosing atopic dermatitis, restoring the skin barrier, controlling inflammation and escalating safely.

reviewed 2026-08-20
Dermatology

Psoriasis assessment and treatment selection

AAD–NPF assessment of cutaneous psoriasis, high-impact sites, psoriatic arthritis, comorbidity, topical care and specialist escalation in US practice.

reviewed 2026-08-20
Dermatology

Scabies recognition, treatment and contact control

CDC-based classic and crusted scabies treatment, simultaneous contact management, environmental measures and post-treatment review.

reviewed 2026-08-20
Dermatology

Tinea corporis, cruris and pedis

CDC-based diagnosis, topical treatment, steroid avoidance, resistant dermatophyte recognition and escalation for common cutaneous tinea.

reviewed 2026-08-20
Dermatology

Phenotype-led rosacea care

National Rosacea Society consensus for diagnosing rosacea by phenotype, selecting feature-specific treatment and recognizing ocular disease.

reviewed 2026-08-20
Dermatology

Alopecia areata recognition and treatment planning

US diagnosis, severity documentation, limited-disease options, referral and current FDA-labeled systemic treatment context for alopecia areata.

reviewed 2026-08-20
Dermatology

Baricitinib for severe alopecia areata

FDA-labeled adult severe-alopecia use of baricitinib, with pretreatment evaluation, risk selection, monitoring and the June 2026 hypoglycemia warning.

reviewed 2026-08-20
Dermatology

Ritlecitinib for severe alopecia areata

June 2026 FDA-labeled use of ritlecitinib for adults and adolescents aged 12 years or older, including baseline testing and JAK-class safety.

reviewed 2026-08-20
Metabolic

Adult overweight and obesity management

US intensive behavioral treatment and obesity pharmacotherapy, with metabolic-surgery eligibility retained as an explicit evidence gap.

reviewed 2026-08-20
Endocrinology / Obesity

Semaglutide (Wegovy) for chronic weight management

Current US Wegovy indications, formulation-specific initiation, monitoring, contraindications and long-term treatment review.

reviewed 2026-08-20
Endocrinology / Obesity

Tirzepatide (Zepbound) for chronic weight management

Current US Zepbound eligibility, dose escalation, monitoring, interactions, reproductive counseling and serious adverse-effect boundaries.

reviewed 2026-08-20
Cardiovascular & renal

Dapagliflozin (Farxiga) for chronic kidney disease

FDA-label and KDIGO positioning, renal-function and volume checks, ketoacidosis prevention, infection safety and peri-procedural planning.

reviewed 2026-08-20
Cardiovascular & renal

Empagliflozin (Jardiance) for chronic kidney disease

FDA-label and KDIGO positioning, kidney and volume assessment, ketoacidosis and infection safety, and coordinated CKD follow-up.

reviewed 2026-08-20
Urgent care

Nosebleed assessment and control

AAO-HNSF first aid, focused examination, packing and cautery principles, antithrombotic safety and referral for epistaxis in patients aged three years or older.

reviewed 2026-08-20
Urgent care

Acute red eye triage in ambulatory care

AAO-based differentiation of uncomplicated conjunctivitis from keratitis and other sight-threatening red-eye presentations, with contact-lens and referral safety.

reviewed 2026-08-20
Infection & public health

Measles recognition, isolation and public-health response

CDC 2026 recognition, immediate airborne precautions, paired PCR and serology, mandatory reporting, supportive care and exposure coordination.

reviewed 2026-08-20
Infection & public health

Child and adolescent immunization review

A safe workflow for applying the current CDC/ACIP age, catch-up, medical-indication and special-situation schedules without freezing a changing vaccine table.

reviewed 2026-08-20
Infection & public health

Adult immunization review

CDC/ACIP age-based, risk-based, pregnancy, catch-up and shared-decision vaccination workflow for US adults.

reviewed 2026-08-20
Sexual health

Syphilis diagnosis, staging and treatment

CDC stage-specific serology, penicillin treatment, pregnancy, neurologic and ocular escalation, partner services and response monitoring.

reviewed 2026-08-20
Sexual health

Gonorrhea testing, treatment and resistance response

CDC anatomic-site testing, weight-based ceftriaxone treatment, chlamydia coverage, pharyngeal test of cure, partner care and suspected resistance escalation.

reviewed 2026-08-20
Public health

HIV preexposure prophylaxis

CDC HIV PrEP eligibility, baseline exclusion of acute HIV, oral and injectable choices, kidney and hepatitis B safety and continuing monitoring.

reviewed 2026-08-20
Infection

HIV nonoccupational postexposure prophylaxis

CDC 2025 emergency nPEP evaluation, prompt three-drug initiation, 28-day completion, exposure-source testing and transition to PrEP.

reviewed 2026-08-20
Infection

Urinary tract infection assessment and stewardship

US-focused differentiation of bladder-limited and systemic urinary infection, selective testing, empiric treatment review and safety escalation.

reviewed 2026-08-20
Infections

Lower urinary tract infection in women

A US pathway for acute cystitis in nonpregnant and pregnant patients, with explicit boundaries for pyelonephritis and asymptomatic bacteriuria.

reviewed 2026-08-20
Infection

Acute sore throat and streptococcal pharyngitis

US risk assessment, selective group A streptococcal testing, antibiotic stewardship and deep-neck-infection safety for children and adults.

reviewed 2026-08-20
Infection

Acute otitis media in children

US pediatric diagnostic criteria, pain treatment, observation options, antimicrobial stewardship and complication escalation.

reviewed 2026-08-20
Infection

Adult rhinosinusitis

US differentiation of viral and bacterial acute rhinosinusitis, shared treatment decisions, chronic-disease confirmation and safety referral.

reviewed 2026-08-20
Infection

Lyme disease prevention, diagnosis and treatment

North American tick-bite risk assessment, erythema migrans diagnosis, staged testing, treatment boundaries and organ-specific escalation.

reviewed 2026-08-20
Infection

Acute cough and uncomplicated bronchitis stewardship

US assessment of acute cough, exclusion of pneumonia, antibiotic avoidance and return precautions for uncomplicated bronchitis.

reviewed 2026-08-20
Infection

Impetigo and ecthyma

US diagnosis, limited-versus-extensive treatment, culture strategy, transmission control and deeper-infection escalation.

reviewed 2026-08-20
Infections

Cellulitis and erysipelas

US distinction of nonpurulent cellulitis from abscess, severity assessment, focused microbiology and necrotizing-infection escalation.

reviewed 2026-08-20
Infection

Acute diffuse otitis externa

US diagnosis, pain control, topical first-line therapy, drop-delivery optimization and malignant-otitis-externa escalation.

reviewed 2026-08-20
Infection

Long COVID clinical assessment and support

CDC-aligned patient-centered evaluation, symptom-directed care, post-exertional-malaise safety and functional support for Long COVID.

reviewed 2026-08-20
Infection

Herpes zoster recognition and early treatment

US diagnosis, timely antiviral treatment, ophthalmic and disseminated-disease escalation, transmission precautions and prevention follow-up.

reviewed 2026-08-20
Infection

Infectious conjunctivitis in adults and children

AAO-aligned differentiation of viral, bacterial and high-risk conjunctivitis, antibiotic stewardship and urgent corneal referral.

reviewed 2026-08-20
Infection

Nirmatrelvir–ritonavir for outpatient COVID-19

US FDA-label and CDC workflow for time-critical Paxlovid eligibility, interaction reconciliation, organ-function dosing and safety follow-up.

reviewed 2026-08-20
Infection

Genital herpes diagnosis, treatment and counseling

CDC-aligned lesion testing, first-episode and recurrent treatment decisions, transmission counseling and pregnancy safety.

reviewed 2026-08-20
Infection

Hepatitis B screening and test interpretation

CDC universal adult triple-panel screening, pregnancy and risk-based testing, result interpretation and linkage to liver care.

reviewed 2026-08-20
Infection

Hepatitis C screening, confirmation and linkage

CDC universal adult and pregnancy screening, antibody-to-RNA confirmation, reinfection testing and linkage to curative treatment.

reviewed 2026-08-20
Infection

HIV screening and diagnostic testing in primary care

USPSTF universal screening, pregnancy testing, repeat risk-based testing, acute-HIV recognition and rapid linkage to care.

reviewed 2026-08-20
Infection

Pertussis recognition, treatment and public-health response

CDC-aligned clinical recognition, nasopharyngeal testing, early treatment, post-exposure prophylaxis and infant-risk escalation.

reviewed 2026-08-20
Infection

Pinworm infection diagnosis and household control

CDC-based tape testing, two-dose treatment logic, household hygiene and special-population precautions for Enterobius vermicularis.

reviewed 2026-08-20
Digestive

Dyspepsia and gastroesophageal reflux disease

US evaluation and treatment of uninvestigated dyspepsia and GERD, including endoscopy triggers, H. pylori testing, proton-pump-inhibitor use and objective testing.

reviewed 2026-08-20
Digestive

Metabolic dysfunction-associated steatotic liver disease

Current US MASLD recognition, noninvasive fibrosis risk stratification, metabolic treatment, referral and cirrhosis surveillance.

reviewed 2026-08-20
Digestive

Irritable bowel syndrome in adults

ACG-based positive diagnosis, focused exclusion testing, diet, subtype-directed treatment and gut–brain behavioral care for IBS.

reviewed 2026-08-20
Digestive

Celiac disease

ACG-based case finding, serology and biopsy diagnosis, gluten-free treatment, nutritional assessment and follow-up for celiac disease.

reviewed 2026-08-20
Digestive

Pharmacologic treatment of chronic idiopathic constipation

The 2023 AGA/ACG medicine recommendations for adults already diagnosed with chronic idiopathic constipation.

reviewed 2026-08-20
Digestive

Hemorrhoidal disease

ASCRS-based evaluation, bowel-habit treatment, office procedures, surgery selection and rectal-bleeding safety for symptomatic hemorrhoids.

reviewed 2026-08-20
Digestive

Anal fissure in adults

ASCRS-based recognition and staged care of acute and chronic anal fissure, including conservative care, topical therapy, botulinum toxin and surgery.

reviewed 2026-08-20
Digestive

Colonic diverticulitis

The 2026 ACG approach to diagnosis, selective outpatient care and antibiotics, recurrence prevention, colon evaluation and individualized surgery.

reviewed 2026-08-20
Digestive

Suspected inflammatory bowel disease in adults

Current US recognition and diagnostic confirmation of ulcerative colitis and Crohn disease, including infection exclusion, endoscopy, imaging and urgent escalation.

reviewed 2026-08-20
Digestive

Evaluation of abnormal liver chemistries

ACG-based confirmation, injury-pattern classification, etiologic evaluation and urgency assessment for abnormal aminotransferases, alkaline phosphatase or bilirubin.

reviewed 2026-08-20
Digestive

Right-upper-quadrant pain and suspected bile-duct stones

A bounded US summary of ACR biliary imaging and ASGE choledocholithiasis risk stratification; operative and antimicrobial management remain outside this source set.

reviewed 2026-08-20
Digestive

Acute pancreatitis

The 2024 ACG pathway for diagnosis, early severity assessment, fluids, feeding, biliary intervention and pancreatic-necrosis management.

reviewed 2026-08-20
Digestive

Acute infectious diarrhea in adults

IDSA-based assessment, rehydration, selective stool testing and antibiotic stewardship for acute diarrhea in US and travel settings.

reviewed 2026-08-20
Digestive

Acute upper gastrointestinal bleeding

ACG-based emergency risk assessment, resuscitation, transfusion, endoscopy, hemostasis and post-endoscopic care for overt upper GI bleeding.

reviewed 2026-08-20
Musculoskeletal

Hand, hip and knee osteoarthritis

ACR/Arthritis Foundation–based nonoperative management for hand, hip and knee osteoarthritis; arthroplasty timing remains an evidence gap.

reviewed 2026-08-20
Musculoskeletal

Low back pain with or without radicular symptoms

VA/DoD-based triage, selective imaging, active rehabilitation, medication stewardship and escalation for acute and chronic low back pain.

reviewed 2026-08-20
Musculoskeletal

Established rheumatoid arthritis: pharmacologic treatment

ACR-based treatment of established rheumatoid arthritis; recognition, diagnostic testing and referral remain an explicit source gap.

reviewed 2026-08-20
Musculoskeletal

Polymyalgia rheumatica

Recognition, exclusion of mimics, glucocorticoid treatment, relapse monitoring and giant-cell-arteritis safety in polymyalgia rheumatica.

reviewed 2026-08-20
Musculoskeletal

Giant cell arteritis

ACR/Vasculitis Foundation–based emergency recognition, diagnostic confirmation, vascular imaging and glucocorticoid-sparing care for GCA.

reviewed 2026-08-20
Musculoskeletal

Established axial spondyloarthritis: treatment

The 2026 ACR treatment update for established axial spondyloarthritis; diagnosis and sacroiliac imaging remain an explicit source gap.

reviewed 2026-08-20
Musculoskeletal

Adult rotator cuff injury

AAOS 2025 evaluation, rehabilitation, injection, imaging and operative decision-making for adult rotator cuff tears.

reviewed 2026-08-20
Musculoskeletal

Carpal tunnel syndrome

AAOS 2024 diagnosis, selective electrodiagnostic testing, splint and injection options, surgical release and postoperative care.

reviewed 2026-08-20
MSK

Gout flares and urate-lowering therapy

ACR-based diagnosis, acute flare treatment, allopurinol-first treat-to-target therapy, prophylaxis and comorbidity-aware care.

reviewed 2026-08-20
Neurology

Headache assessment and primary-headache classification

US-focused secondary-headache triage, phenotype diagnosis, selective testing, medication-overuse prevention and follow-up.

reviewed 2026-08-20
Neurology

Migraine acute treatment and prevention

US individualized acute and preventive migraine care, medication-overuse control, reproductive safety and escalation.

reviewed 2026-08-20
Neurology

Adult first unprovoked seizure: prognosis and treatment decision

AAN/AES evidence on recurrence prognosis and whether to start immediate treatment after an adult first unprovoked seizure.

reviewed 2026-08-20
Neurology

Benign paroxysmal positional vertigo

US bedside diagnosis, canalith repositioning, low-value-test avoidance, fall-risk assessment and central-vertigo escalation.

reviewed 2026-08-20
Neurology

Bell's palsy recognition and early care

US exclusion of stroke and structural causes, time-sensitive corticosteroid treatment, corneal protection and follow-up.

reviewed 2026-08-20
Neurology

Adult age-related hearing loss identification and care

US screening, otoscopy, audiologic confirmation, communication support, amplification and urgent asymmetric-loss referral.

reviewed 2026-08-20
Neurology

Tinnitus assessment and quality-of-life management

US red-flag assessment, audiology, education, sound strategies, cognitive behavioral care and low-value-treatment avoidance.

reviewed 2026-08-20
Neurology

Trigeminal neuralgia recognition and specialist treatment

US phenotype recognition, structural-cause evaluation, medication safety and neurosurgical referral for trigeminal neuralgia.

reviewed 2026-08-20
Neurology

Cognitive decline and dementia diagnostic evaluation

US patient-centered recognition, tiered evaluation, collateral history, diagnosis disclosure and early care planning for suspected dementia.

reviewed 2026-08-20
Neurology

Parkinson disease diagnosis and early motor treatment

US recognition, movement-specialist confirmation, initial dopaminergic treatment and adverse-effect monitoring for early Parkinson disease.

reviewed 2026-08-20
Neurology

Multiple sclerosis diagnosis and disease-modifying care

US application of the 2024 McDonald criteria, specialist confirmation, individualized disease-modifying therapy and longitudinal safety monitoring.

reviewed 2026-08-20
Neurology

Distal symmetric polyneuropathy evaluation

A source-bounded AAN summary of laboratory and genetic testing in distal symmetric polyneuropathy; broader management remains blocked.

reviewed 2026-08-20
Neurology

Amyotrophic lateral sclerosis recognition and multidisciplinary care

US urgent recognition, specialist diagnosis, respiratory and nutrition surveillance, multidisciplinary care and preference-sensitive planning for ALS.

reviewed 2026-08-20
Mental health & neurodevelopmental

Pediatric ADHD diagnosis and longitudinal treatment

AAP-aligned multi-setting evaluation, comorbidity assessment, age-specific behavioral and medication treatment, school support and monitoring.

reviewed 2026-08-20
Mental health & neurodevelopmental

Adult autism: federal source-scope boundary

What the attached CDC diagnostic page and HHS lifespan-services research plan do and do not establish for adult autism care.

reviewed 2026-08-20
Mens health

Lower urinary tract symptoms attributed to benign prostatic hyperplasia

AUA-based evaluation and shared medical or procedural management of bothersome LUTS attributed to benign prostatic hyperplasia.

reviewed 2026-08-20
Mens health

Male lower urinary tract symptoms: differential and initial pathway

A symptom-led US approach separating bladder storage, outlet obstruction, infection, neurologic dysfunction and retention before treatment.

reviewed 2026-08-20
Mens health

Erectile dysfunction

AUA-based evaluation of erectile dysfunction as a sexual-health and cardiovascular-risk marker, with staged shared treatment.

reviewed 2026-08-20
Mens health

Acute epididymitis and epididymo-orchitis

CDC-based torsion exclusion, STI and urinary testing, organism-directed empiric therapy, partner care and follow-up.

reviewed 2026-08-20
Mens health

Acute nontraumatic scrotal pain: imaging evidence boundary

ACR imaging appropriateness for acute scrotal pain, with operative torsion management kept outside the attached source scope.

reviewed 2026-08-20
Women's health

Menopause symptom assessment and treatment

The Menopause Society approach to individualized hormone and evidence-based nonhormone treatment for bothersome menopausal symptoms.

reviewed 2026-08-20
Women's health

Heavy menstrual bleeding and abnormal uterine bleeding

ACOG-based diagnosis and acute abnormal-uterine-bleeding management; chronic stable treatment remains an explicit source gap.

reviewed 2026-08-20
Women's health

Suspected endometriosis: diagnosis and initial pathway

ACOG 2026 diagnostic guidance for clinical recognition, imaging, presumptive diagnosis and timely shared decisions without mandatory diagnostic surgery.

reviewed 2026-08-20
Women's health

Hypertensive disorders of pregnancy

ACOG differentiation of chronic and gestational hypertension, preeclampsia surveillance, severe-feature escalation and CHAP-informed treatment.

reviewed 2026-08-20
Women's health

Diabetes before, during and after pregnancy

ADA 2026 preconception optimization, pregnancy glucose monitoring, insulin-first pharmacotherapy, technology and postpartum follow-up.

reviewed 2026-08-20
Women's health

Urinary incontinence and pelvic organ prolapse

ACOG/AUGS symptom-led evaluation, conservative care and referral boundaries for urinary leakage and pelvic organ prolapse.

reviewed 2026-08-20
Women's health

Bacterial vaginosis

CDC diagnosis and treatment of symptomatic bacterial vaginosis with the 2025 ACOG recurrent-BV partner-therapy update.

reviewed 2026-08-20
Women's health

Vulvovaginal candidiasis

CDC differentiation of uncomplicated, recurrent, severe and non-albicans vulvovaginal candidiasis with pregnancy and resistance boundaries.

reviewed 2026-08-20
Women's health

Pelvic inflammatory disease

CDC low-threshold diagnosis, empiric broad treatment, hospitalization criteria, partner care and 72-hour response review for acute PID.

reviewed 2026-08-20
Women's health

Uncomplicated chlamydial infection

CDC testing, site-specific treatment, pregnancy follow-up, partner management and repeat testing for uncomplicated chlamydial infection.

reviewed 2026-08-20
Women's health

Emergency contraception

CDC U.S. SPR timing, method selection, post-ulipristal contraception and follow-up after emergency contraception.

reviewed 2026-08-20
Women's health

Ectopic pregnancy and early pregnancy loss

ACOG evaluation of pregnancy of unknown location, ectopic-pregnancy urgency and patient-centered management of confirmed early pregnancy loss.

reviewed 2026-08-20
Women's health

Combined hormonal contraception

CDC eligibility screening, person-centered initiation, backup and safety follow-up for pills, patches and vaginal rings.

reviewed 2026-08-20
Women's health

Progestin-only pills

CDC method-specific eligibility, initiation, missed-pill instructions and follow-up for US progestin-only oral contraception.

reviewed 2026-08-20
Women's health

Long-acting reversible contraception

CDC person-centered initiation and follow-up for intrauterine devices, contraceptive implants and injectable contraception.

reviewed 2026-08-20
Women's health

Polycystic ovary syndrome

2023 international PCOS diagnostic criteria, life-course risk assessment and goal-directed reproductive, metabolic and symptom management.

reviewed 2026-08-20
Women's health

Prepregnancy counseling

ACOG and ASRM preparation for pregnancy through reproductive goals, condition and medication optimization, prevention and equitable risk review.

reviewed 2026-08-20
Women's health

Recurrent pregnancy loss

ASRM 2026 definition, evidence-based staged evaluation, cause-directed treatment and prognosis after recurrent pregnancy loss.

reviewed 2026-08-20
Cancer & referral

Possible cancer in primary care: symptom-led evaluation

A US symptom-led safety framework for investigating possible cancer without imposing one universal referral clock across organ systems.

reviewed 2026-08-20
Cancer & referral

Elevated PSA and suspected prostate cancer

AUA/SUO 2026 shared decision, repeat-PSA and risk-adapted urology pathway for possible clinically significant prostate cancer.

reviewed 2026-08-20
Cancer & referral

Gross and microscopic hematuria

AUA/SUFU 2025 confirmation, risk stratification, cystoscopy and upper-tract evaluation for adult hematuria.

reviewed 2026-08-20
Cancer & referral

Palpable breast mass: initial imaging and referral

Age- and context-matched ACR imaging, clinical–radiologic concordance and tissue diagnosis for a new palpable breast finding.

reviewed 2026-08-20
Cancer & referral

Rectal bleeding and iron-deficiency anemia evaluation

A source-bounded US summary of iron-deficiency-anemia evaluation and rectal bleeding when hemorrhoids are suspected; broader cancer symptoms remain blocked.

reviewed 2026-08-20
Cancer & referral

Suspicious skin lesions: recognition, biopsy and referral

Symptom-led recognition and tissue diagnosis of melanoma and keratinocyte cancer, distinct from population screening.

reviewed 2026-08-20
Cancer & referral

Possible ovarian cancer and adnexal mass

US ovarian-screening limits and ACR adnexal-mass imaging; oncology referral and procedural planning remain explicit evidence gaps.

reviewed 2026-08-20
Cancer & referral

Metastatic epidural spinal cord or cauda-equina compression

Emergency recognition, MRI, corticosteroid and multidisciplinary surgical–radiation management of malignant neural compression.

reviewed 2026-08-20
Mental health

Major depressive disorder assessment and treatment

VA/DoD-aligned adult depression assessment, shared treatment selection, measurement-based follow-up and urgent risk escalation.

reviewed 2026-08-20
Mental health

Adult anxiety-disorder screening

USPSTF preventive-screening guidance for anxiety disorders in asymptomatic adults, including age limits and the required diagnostic follow-through.

reviewed 2026-08-20
Mental health

ME/CFS recognition and symptom-prioritized care

CDC-bounded recognition of post-exertional malaise, exclusion of alternatives, energy management and support for severe disease.

reviewed 2026-08-20
Mental health

Chronic insomnia disorder assessment and treatment

VA/DoD-aligned clinical diagnosis, CBT-I first-line care, selective sleep testing and medication safety review.

reviewed 2026-08-20
Mental health

Daridorexant for adult insomnia

US FDA-label boundaries for daridorexant placed within CBT-I-first chronic-insomnia assessment and follow-up.

reviewed 2026-08-20
Mental health / Addiction

Alcohol misuse and alcohol use disorder

VA/DoD-aligned screening, diagnostic assessment, withdrawal triage, evidence-based treatment and longitudinal harm reduction.

reviewed 2026-08-20
Mental health

Bipolar disorder diagnosis and episode management

VA/DoD-aligned diagnostic triage, phase-specific treatment, maintenance planning and high-risk escalation for adult bipolar disorder.

reviewed 2026-08-20
Mental health

First-episode psychosis and schizophrenia care

VA/DoD-aligned early recognition, medical and substance differential, coordinated specialty care and antipsychotic safety monitoring.

reviewed 2026-08-20
Mental health

Eating-disorder assessment and treatment planning

APA-aligned comprehensive assessment, medical-stability triage, diagnosis-specific psychotherapy and coordinated nutrition rehabilitation.

reviewed 2026-08-20
Mental health

Suicide-related self-harm assessment and safety planning

VA/DoD-aligned identification, comprehensive suicide-risk assessment, collaborative safety planning and risk-tailored disposition.

reviewed 2026-08-20
Mental health

PTSD assessment and evidence-based treatment

VA/DoD-aligned diagnostic assessment, trauma-focused psychotherapy, selected pharmacotherapy and comorbidity-aware follow-up.

reviewed 2026-08-20
Mental health

Perinatal mental-health screening and treatment

ACOG-aligned universal screening with care systems, bipolar assessment, individualized treatment and emergency postpartum escalation.

reviewed 2026-08-20
Acute medicine / Older people

Delirium: recognition, cause-finding and safer management

A deliberately bounded AGS postoperative and SCCM ICU delirium summary with multicomponent care and source-specific medication limits.

reviewed 2026-08-20
Acute medicine / Older people

Iron-deficiency anemia: confirmation, cause and replacement

AGA-based confirmation, bleeding and malabsorption investigation, oral or intravenous iron and response monitoring.

reviewed 2026-08-20
Acute medicine / Older people

Falls assessment and prevention in older adults

USPSTF and CDC STEADI risk identification, injury assessment, exercise and individualized multifactorial intervention.

reviewed 2026-08-20
Acute medicine / Older people

Older adults with multimorbidity: priorities and coordinated decisions

AGS priority-, trajectory- and burden-aware decisions when multiple disease guidelines and treatments conflict.

reviewed 2026-08-20
Hematology

Vitamin B12 and folate deficiency anemia

NIH biochemical evidence and current US label safety for assessment and replacement of vitamin B12 and folate deficiency.

reviewed 2026-08-20
Vascular / Dermatology

Symptomatic lower-extremity varicose veins

North American multisociety evaluation, duplex confirmation, conservative options and preference-sensitive superficial venous intervention.

reviewed 2026-08-20
Vascular / Dermatology

Chronic leg-ulcer infection: source boundary

A transparent account of why the attached US society records do not establish a current chronic leg-ulcer infection pathway.

reviewed 2026-08-20
Vascular / Dermatology

Raynaud's phenomenon recognition and triage

ACR educational recognition material for Raynaud phenomenon, with testing and medication selection kept outside the source scope.

reviewed 2026-08-20
Vascular / Dermatology

Venous leg-ulcer management: archived-source boundary

A source-status summary explaining why the attached society records do not support a current active venous-leg-ulcer management pathway.

reviewed 2026-08-20
Pain

Chronic noncancer pain assessment and safer treatment

US person-centered chronic-pain evaluation, multimodal nonopioid care and flexible CDC/VA-DoD opioid safety principles.

reviewed 2026-08-20
Pain

Painful diabetic polyneuropathy treatment

AAN guidance on oral, topical and nonpharmacologic treatment options for adults with established painful diabetic polyneuropathy.

reviewed 2026-08-20
Palliative care

Palliative care and end-of-life planning

US serious-illness palliative assessment, symptom and caregiver support, advance-care planning and clear separation from the Medicare hospice benefit.

reviewed 2026-08-20
Emergency / Allergy

Anaphylaxis recognition, emergency treatment and follow-up

JTFPP-based immediate epinephrine treatment, physiologic support, observation decisions and prevention after anaphylaxis.

reviewed 2026-08-20
Emergency / Allergy

Urticaria and angioedema outside anaphylaxis

Acute urticaria phenotype, important mimics and emergency safety boundaries, with chronic drug sequencing kept outside scope.

reviewed 2026-08-20
Emergency / Allergy

Head injury assessment and early management

Age-appropriate emergency assessment, selective imaging, safe discharge and graded recovery using current ACEP and CDC sources.

reviewed 2026-08-20
Public health / Prevention

Tobacco smoking dependence assessment and treatment

USPSTF and ATS-informed behavioral support, pharmacotherapy and longitudinal relapse care with pregnancy and vaping evidence boundaries.

reviewed 2026-08-20
Public health / Prevention

Medication reconciliation and safer transitions

AHRQ-based medication-history verification, discrepancy resolution, transition communication and federal adverse-event reporting.

reviewed 2026-08-20
Safeguarding

Recognition and evaluation of suspected child physical abuse

AAP-based recognition, trauma-informed examination and documentation, protective reporting and state-law boundaries.

reviewed 2026-08-20
Infection & safety

Suspected sepsis and septic shock

Current adult and pediatric Surviving Sepsis Campaign priorities for immediate recognition, resuscitation, antimicrobials, source control, reassessment and US hospital implementation.

reviewed 2026-08-20
Infection & safety

Fever in children younger than 5 years

Age-stratified US assessment of a febrile young child, with separate pathways for young infants, source-directed evaluation, sepsis screening and safe disposition.

reviewed 2026-08-20
Infection & safety

Meningococcal disease: CDC clinical guidance

Current CDC recognition, diagnostic testing, empiric treatment and carriage-eradication guidance for suspected meningococcal disease.

reviewed 2026-08-20
Pediatrics

Bronchiolitis in infants and young children

Clinical diagnosis and supportive management of uncomplicated bronchiolitis, with explicit exclusion criteria and escalation for respiratory failure, apnea or dehydration.

reviewed 2026-08-20
Pediatrics

Acute gastroenteritis and dehydration in children younger than 5 years

Hydration-first management with source-directed stool testing, early nutrition, antimicrobial stewardship and escalation for shock or a surgical presentation.

reviewed 2026-08-20
Pediatrics

Viral croup: assessment and management

Severity-based management of barking cough and stridor with minimal agitation, corticosteroid treatment, nebulized epinephrine when indicated and airway escalation.

reviewed 2026-08-20
Pediatrics

Urinary tract infection in children and adolescents

Probability-based urine testing, uncontaminated collection, urinalysis-plus-culture diagnosis, local antimicrobial selection, result follow-up and selective imaging.

reviewed 2026-08-20
Pediatrics

Functional constipation in children and adolescents

Current AGA–NASPGHAN assessment and stepwise care emphasizing clinical diagnosis, alarm features, disimpaction, maintenance, behavioral support and escalation.

reviewed 2026-08-20
Pediatrics

Neonatal hyperbilirubinemia in infants born at 35 weeks or later

AAP 2022 bilirubin measurement, hour-specific risk assessment, feeding support, follow-up and urgent escalation for infants born at 35 weeks or later.

reviewed 2026-08-20
Pediatrics

Febrile seizures in young children

Classification, emergency seizure care, fever-source assessment, restraint in testing after a simple event and escalation after complex or atypical seizures.

reviewed 2026-08-20