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Medicines naloxone hydrochloride + oxycodone hydrochlorideQuestion & answer

naloxone hydrochloride + oxycodone hydrochloride · Medicine question

Can naloxone hydrochloride + oxycodone hydrochloride be stopped suddenly?

iatroX medicinesPublished 21 August 2026Reviewed 21 August 2026

The answer

Answer

Sudden cessation can cause withdrawal symptoms. Stopping should follow an individual plan agreed with the prescriber.

Sources for this answer

Oxycodone hydrochloride/Naloxone hydrochloride 10 mg/5 mg prolonged-release tabletsemc · SmPC Current selected SmPC · Version 1
NHSNHS · NHS medicine guidance

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The full medicine guide

naloxone hydrochloride + oxycodone hydrochloride

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