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Medicines calcium folinate hydrateQuestion & answer

calcium folinate hydrate · Medicine question

Can it increase seizures?

iatroX medicinesPublished 19 August 2026Reviewed 19 August 2026

The answer

Answer

Yes. It may reduce the effects of phenytoin, phenobarbital, primidone or succinimides and increase seizure frequency in susceptible people.

Sources for this answer

Calcium Folinate 10 mg/ml Injectionemc · SmPC Current selected SmPC · Version 18
Calcium Folinate 15mg Tabletsemc · SmPC Current selected SmPC · Version 14

Calcium folinate 10 mg/ml solution for injection/infusion

emc · SmPC Current selected SmPC · Version 1

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The full medicine guide

calcium folinate hydrate

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Read the calcium folinate hydrate guide

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