Answer
The Hospira UK Ltd methotrexate 25 mg/ml injection product can be administered intravenously, intramuscularly, intraarterially or intrathecally, but only the 50 mg/2 ml presentation should be used intrathecally because larger-volume presentations risk accidental overdose.
Sources for this answer
- Methotrexate 25 mg/ml InjectionHospira UK Ltd · emc · SmPC §4.2 Posology and method of administration · Version 27Document updated
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