Answer
Janumet (metformin + sitagliptin) is contraindicated in severe renal failure, defined as a glomerular filtration rate (GFR) below 30 mL/min.
Sources for this answer
- Janumet 50 mg/1000 mg film-coated tabletsMerck Sharp & Dohme (UK) Limited · emc · SmPC §4.3 Contraindications · Version 26Document updated
Sources checked