Answer
TISSEEL contains aprotinin, and later exposure can cause severe hypersensitivity even if an earlier application was tolerated. Recording use also supports product-batch traceability.
Sources for this answer
- TISSEEL Ready to use Solutions for Sealant — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.