Answer
Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Gilead should not be started during pregnancy because reduced cobicistat levels and insufficient boosting in the second and third trimesters lower elvitegravir exposure, potentially causing virological failure and increased mother-to-child HIV transmission.
Sources for this answer
- Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Gilead 150mg/150mg/200mg/10mg film coated tabletsGilead Sciences Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 37Document updated
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