Answer
Simvastatin is contraindicated with Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Gilead because co-administration may increase plasma concentrations of CYP3A-metabolised simvastatin, risking serious or life-threatening myopathy, including rhabdomyolysis.
Sources for this answer
- Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Gilead 150mg/150mg/200mg/10mg film coated tabletsGilead Sciences Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 37Document updated
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