Answer
Syndol must not be taken while breastfeeding because codeine and its active metabolites can enter breast milk, and mothers who are CYP2D6 ultra-rapid metabolisers may produce higher milk levels of active metabolites, very rarely causing potentially fatal opioid toxicity in the infant.
Sources for this answer
- Syndol Film-coated TabletsPhoenix Labs · emc · SmPC §4.6 Fertility, pregnancy and lactation · Version 6Document updated
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