Answer
Amikacin must not be used in patients with myasthenia gravis because its potential curare-like effect on the neuromuscular junction may aggravate muscle weakness, with neuromuscular blockade and respiratory paralysis reported with aminoglycosides.
Sources for this answer
- Amikacin 250 mg/ml InjectionHospira UK Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 19Document updated
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