Answer
Taking Zepatier with rifampicin is contraindicated because rifampicin inhibits OATP1B, which may significantly increase grazoprevir plasma concentrations.
Sources for this answer
- ZEPATIER 50 mg/100 mg film coated tabletsMerck Sharp & Dohme (UK) Limited · emc · SmPC §4.3 Contraindications · Version 13Document updated
- ZEPATIER 50 mg/100 mg film coated tablets