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Medicines elbasvir + grazoprevirQuestion & answer

elbasvir + grazoprevir · Medicine question

Can Zepatier be taken with carbamazepine or phenytoin?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Zepatier must not be taken with carbamazepine or phenytoin because co-administration is contraindicated.

Sources for this answer

ZEPATIER 50 mg/100 mg film coated tabletsMerck Sharp & Dohme (UK) Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 13Document updated 5 February 2024

Sources checked 8 November 2026

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The full medicine guide

More questions about elbasvir + grazoprevir

Why is close INR monitoring recommended when Zepatier is taken with vitamin K antagonists?What interaction may occur between Zepatier and dabigatran etexilate?For which hepatitis C genotypes is Zepatier not recommended because efficacy has not been demonstrated?How much lactose and sodium does each Zepatier film-coated tablet contain?How often did ALT elevations above five times the upper limit of normal occur in clinical studies of Zepatier with or without ribavirin?

elbasvir + grazoprevir

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What is Zepatier used to treat, and which age and weight groups is it indicated for?