Answer
Taking St John's wort with Alyftrek is not recommended because it induces CYP3A, which may reduce exposure to Alyftrek’s active components and reduce its efficacy.
Sources for this answer
- Alyftrek 50 mg/20 mg/4 mg film-coated tabletsVertex Pharmaceuticals (Europe) Limited · emc · SmPC §4.5 Interaction with other medicinal products · Version 4Document updated
Sources checked