Answer
Taking Ryeqo with erythromycin is not recommended because erythromycin inhibits P-glycoprotein and moderately inhibits CYP3A4, increasing relugolix exposure (AUC) 4.1-fold and its maximum concentration 3.8-fold in an interaction study.
Sources for this answer
- Ryeqo 40mg/1mg/0.5mg film-coated tabletsGedeon Richter (UK) Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 6Document updated
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