Answer
Taking rifampicin with Tavlesse (fostamatinib) is not recommended because rifampicin strongly induces CYP3A4, decreasing exposure to the active metabolite R406 and potentially reducing efficacy.
Sources for this answer
- Tavlesse 100 mg film-coated tabletsGrifols UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 3Document updated
Sources checked