Answer
Tavlesse (fostamatinib) 100 mg twice daily with a single 40 mg simvastatin dose increased simvastatin AUC by 64% and Cmax by 113%, and simvastatin acid AUC by 66% and Cmax by 83%.
Sources for this answer
- Tavlesse 100 mg film-coated tabletsGrifols UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 3Document updated
Sources checked