Answer
Taking ivabradine with clarithromycin is contraindicated because clarithromycin is a potent CYP3A4 inhibitor, which increases ivabradine plasma concentrations and may increase the risk of excessive bradycardia.
Sources for this answer
- Ivabradine 5 mg Film-coated TabletsViatris (formerly Mylan or Upjohn) · emc · SmPC §4.5 Interaction with other medicinal products · Version 1Document updated
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