Answer
Taking fostemsavir tromethamine with rifampicin is contraindicated because rifampicin strongly induces CYP3A4, significantly reducing plasma concentrations of temsavir and potentially causing loss of virologic response to fostemsavir.
Sources for this answer
- Rukobia 600 mg prolonged-release tabletsViiV Healthcare UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 6Document updated
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