Answer
Fostemsavir tromethamine increases rosuvastatin plasma concentrations through OATP1B1/3 and/or BCRP inhibition by temsavir, so the lowest possible starting dose of rosuvastatin should be used with careful monitoring.
Sources for this answer
- Rukobia 600 mg prolonged-release tabletsViiV Healthcare UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 6Document updated
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