Answer
Stavudine is not recommended with Combivir (lamivudine + zidovudine) because antagonism of anti-HIV activity between stavudine and zidovudine observed in vitro could reduce the efficacy of both drugs.
Sources for this answer
- Combivir 150 mg/300 mg Film-coated TabletsViiV Healthcare UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 42Document updated
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