Answer
St John's wort is contraindicated with Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Gilead because it induces CYP3A, potentially substantially lowering cobicistat and elvitegravir plasma concentrations and causing loss of therapeutic effect and development of resistance.
Sources for this answer
- Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Gilead 150mg/150mg/200mg/10mg film coated tabletsGilead Sciences Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 37Document updated
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