Answer
Paroxetine inhibits hepatic CYP450 2D6 and can elevate thioridazine plasma levels; thioridazine alone can prolong the QTc interval, causing serious ventricular arrhythmias such as torsades de pointes and sudden death.
Sources for this answer
- Paroxetine 30 mg TabletsSandoz Limited · emc · SmPC §4.3 Contraindications · Version 14Document updated
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