Answer
In premenopausal breast cancer, goserelin suppresses ovarian oestrogen production so an aromatase inhibitor can work in a low-oestrogen environment. Ovarian suppression should be confirmed where required.
Sources for this answer
- Zoladex 3.6mg Implant — Current selected SmPCemc · Summary of Product Characteristics
- Zoladex LA 10.8mg — Current selected SmPCemc · Summary of Product Characteristics
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