Answer
Yes. The initial hormone rise can temporarily worsen bone pain or other tumour symptoms before hormone suppression develops. Report significant or persistent deterioration promptly.
Sources for this answer
- Zoladex 3.6mg Implant — Current selected SmPCemc · Summary of Product Characteristics
- Zoladex LA 10.8mg — Current selected SmPCemc · Summary of Product Characteristics
General medicine information. Follow the instructions for your own medicine and speak to a pharmacist or clinician about your individual circumstances.