isotretinoin · Medicine question

Why is isotretinoin contraindicated during pregnancy?

iatroX medicinesPublished 8 November 2026

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Isotretinoin is contraindicated during pregnancy because it is a powerful human teratogen that causes a high frequency of severe and life-threatening birth defects.

Sources for this answer

Isotretinoin 10 mg soft capsulesRanbaxy (UK) Limited a Sun Pharmaceutical Company · emc · SmPC §4.4 Special warnings and precautions for use · Version 10Document updated 2 February 2026

Sources checked 8 November 2026

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