Why is folic acid used in sickle-cell anaemia?

iatroX medicinesPublished 13 August 2026Reviewed 13 August 2026

The answer

Answer

Ongoing red-blood-cell breakdown increases folate use, so supplementation may help prevent deficiency.

Folic acid Colonis 1mg/ml oral solutionemc · SmPC Current selected SmPC · Version 4
NHSNHS · NHS medicine guidance

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folic acid · Medicine question

iatroX medicinesPublished 13 August 2026Reviewed 13 August 2026

The answer

Ongoing red-blood-cell breakdown increases folate use, so supplementation may help prevent deficiency.

Folic acid Colonis 1mg/ml oral solutionemc · SmPC Current selected SmPC · Version 4
NHSNHS · NHS medicine guidance

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