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Medicines folic acidQuestion & answer

folic acid · Medicine question

Can folic acid be used with methotrexate?

iatroX medicinesPublished 13 August 2026Reviewed 13 August 2026

The answer

Answer

It is sometimes intentionally co-prescribed to reduce adverse effects, but follow the methotrexate clinician's instructions.

Sources for this answer

NHS Specialist Pharmacy ServiceNHS Specialist Pharmacy Service · NHS medicine guidance
Folic acid Colonis 1mg/ml oral solutionemc · SmPC Current selected SmPC · Version 4

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folic acid

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