Answer
Therapeutic digoxin concentration monitoring is recommended because Ledipasvir/Sofosbuvir Gilead may increase digoxin concentrations through P-gp inhibition, although the interaction has not been studied.
Sources for this answer
- Ledipasvir/Sofosbuvir Gilead 90 mg/400 mg film-coated tabletsGilead Sciences Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 6Document updated
Sources checked