Answer
Combining Plasma-Lyte 148 & Glucose 5% w/v with the potassium-sparing diuretic spironolactone is not recommended because it can increase plasma potassium and cause severe, potentially fatal hyperkalaemia, particularly in patients with severe renal insufficiency.
Sources for this answer
- Plasma-Lyte 148 & Glucose 5% w/v solution for infusionBaxter Healthcare Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 5Document updated
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