Answer
Caution is required when fampridine is used with metformin because metformin is a substrate of OCT2, the transporter responsible for active renal secretion of fampridine.
Sources for this answer
- Fampyra 10 mg prolonged-release tabletsMerz Pharma UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 16Document updated
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