Answer
Amlodipine + perindopril is contraindicated with sacubitril/valsartan because simultaneous ACE and neprilysin inhibition increases the risk of angioedema.
Sources for this answer
- Perindopril/Amlodipine KRKA 8mg/10mg tabletsKrka UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 1Document updated
Sources checked