amlodipine + perindopril · Medicine question

What electrolyte disturbance can occur when amlodipine + perindopril is taken with co-trimoxazole?

Name: What electrolyte disturbance can occur when amlodipine + perindopril is taken with co-trimoxazole?
Published: 2026-11-08T01:35:29.338Z

iatroX medicinesPublished 8 November 2026

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Taking amlodipine + perindopril with co-trimoxazole (trimethoprim/sulfamethoxazole) can increase the risk of hyperkalaemia, meaning high blood potassium.

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Perindopril/Amlodipine KRKA 8mg/10mg tabletsKrka UK Ltd · emc · SmPC §4.5 Interaction with other medicinal products · Version 1Document updated 25 January 2024

Sources checked 8 November 2026

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