Answer
Mycophenolic acid in Myfortic inhibits inosine monophosphate dehydrogenase, blocking de novo guanosine nucleotide synthesis, on which T- and B-lymphocytes critically depend for proliferation, whereas other cells can use salvage pathways.
Sources for this answer
- MYFORTIC gastro-resistant tabletsNovartis Pharmaceuticals UK Ltd · emc · SmPC §5.1 Pharmacodynamic properties · Version 26Document updated
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