Why does the benzalkonium chloride in Alomide (lodoxamide trometamol) eye drops warrant caution in patients with dry eyes or a compromised cornea?

The benzalkonium chloride in Alomide (lodoxamide trometamol) eye drops warrants caution in patients with dry eyes or a compromised cornea because it has been reported to cause eye irritation and dry-eye symptoms and may affect the tear film and corneal surface.