Answer
Pancreatic insufficiency can reduce glycerol phenylbutyrate effectiveness because low or absent pancreatic enzymes impair its digestion and release of absorbable active phenylbutyrate, potentially reducing phenylbutyrate absorption and plasma ammonia control.
Sources for this answer
- RAVICTI 1.1 g/ml oral liquidImmedica · emc · SmPC §4.4 Special warnings and precautions for use · Version 7Document updated
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