Answer
Glycerol phenylbutyrate decreases systemic exposure to midazolam by approximately 32% and increases exposure to its 1-hydroxy metabolite, suggesting CYP3A4 induction with steady-state dosing.
Sources for this answer
- RAVICTI 1.1 g/ml oral liquidImmedica · emc · SmPC §4.5 Interaction with other medicinal products · Version 7Document updated
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