tenofovir alafenamide fumarate · Medicine question

Why are itraconazole and ketoconazole not recommended with Vemlidy (tenofovir alafenamide fumarate)?

Name: Why are itraconazole and ketoconazole not recommended with Vemlidy (tenofovir alafenamide fumarate)?
Published: 2026-11-08T02:02:59.724Z

iatroX medicinesPublished 8 November 2026

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Itraconazole and ketoconazole are not recommended with Vemlidy (tenofovir alafenamide fumarate) because they strongly inhibit P-glycoprotein and may increase tenofovir alafenamide plasma concentrations.

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Vemlidy 25 mg film coated tabletsGilead Sciences Ltd · emc · SmPC §4.4 Special warnings and precautions for use · Version 16Document updated 27 February 2025

Sources checked 8 November 2026

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