What bone mineral density changes have been reported in children aged at least 6 years and weighing at least 25 kg taking Vemlidy (tenofovir alafenamide fumarate)?

Some children aged at least 6 years and weighing at least 25 kg receiving Vemlidy (tenofovir alafenamide fumarate) for 48 weeks had reductions of at least 4% in lumbar spine and whole-body bone mineral density; long-term effects on growing bone, including fracture risk, are uncertain.