bosentan monohydrate · Medicine question

Which receptors does bosentan block?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Bosentan blocks both endothelin A (ETA) and endothelin B (ETB) receptors, with slightly higher affinity for ETA receptors, and does not bind to other receptors.

Sources for this answer

Bosentan Milpharm 125 mg film-coated tabletsAurobindo Pharma - Milpharm Ltd. · emc · SmPC §5.1 Pharmacodynamic properties · Version 11Document updated 24 April 2026

Sources checked 8 November 2026

Explore this learning need in CPDTake this topic to CPD, then choose your learning context and available question library.

How common is oedema or fluid retention during bosentan treatment?How does rifampicin affect bosentan plasma concentrations?How long does bosentan take to reach maximum plasma concentrations after oral administration in healthy subjects?How much sodium does each tablet of the Aurobindo Pharma - Milpharm Ltd. bosentan 125 mg film-coated tablet product contain?How often are pregnancy tests recommended for women of childbearing potential taking bosentan?

loading page…

Answer

Sources for this answer

More questions about bosentan monohydrate

Answer

Sources for this answer

More questions about bosentan monohydrate

bosentan monohydrate

More clinical questions?