Which patients with COPD is Seretide Accuhaler 50/500 micrograms indicated to treat?

Seretide Accuhaler 50/500 micrograms is indicated for symptomatic treatment of patients with COPD whose pre-bronchodilator FEV1 is below 60% of predicted normal, who have a history of repeated exacerbations and significant symptoms despite regular bronchodilator therapy.