Which opioid receptors do the ingredients in naloxone hydrochloride + oxycodone hydrochloride act on?

In naloxone hydrochloride + oxycodone hydrochloride, both ingredients have affinity for kappa, mu and delta opioid receptors in the brain, spinal cord and peripheral organs; oxycodone is an agonist at these receptors, whereas naloxone is a pure antagonist at all opioid receptor types.