Answer
In azelastine hydrochloride/fluticasone propionate nasal spray, fluticasone propionate is metabolised principally by hepatic CYP3A4, while azelastine is metabolised by various CYP isoenzymes, mainly CYP3A4, CYP2D6 and CYP2C19.
Sources for this answer
- Flomister 137 micrograms / 50 micrograms per actuation nasal spray, suspensionStrides Pharma UK Ltd · emc · SmPC §5.2 Pharmacokinetic properties · Version 1Document updated
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