Which kinase targets does sorafenib inhibit in tumour blood vessels?

iatroX medicinesPublished 8 November 2026

The answer

Answer

Sorafenib inhibits CRAF, VEGFR-2, VEGFR-3 and PDGFR-ß in tumour blood vessels.

Nexavar 200mg film-coated tabletsBayer plc · emc · SmPC §5.1 Pharmacodynamic properties · Version 32Document updated 27 November 2025

Sources checked 8 November 2026

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sorafenib tosilate · Medicine question

iatroX medicinesPublished 8 November 2026

The answer

Sorafenib inhibits CRAF, VEGFR-2, VEGFR-3 and PDGFR-ß in tumour blood vessels.

Nexavar 200mg film-coated tabletsBayer plc · emc · SmPC §5.1 Pharmacodynamic properties · Version 32Document updated 27 November 2025

Sources checked 8 November 2026

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