Answer
Neomycin decreases exposure to sorafenib tosilate by interfering with sorafenib's enterohepatic recycling; in healthy volunteers, a five-day neomycin regimen reduced average sorafenib exposure by 54%.
Sources for this answer
- Nexavar 200mg film-coated tabletsBayer plc · emc · SmPC §4.5 Interaction with other medicinal products · Version 32Document updated
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