Answer
In vitro and in vivo studies indicate that isavuconazole, the active form of isavuconazonium sulfate, is metabolised by CYP3A4, CYP3A5 and subsequently uridine diphosphate-glucuronosyltransferases (UGT).
Sources for this answer
- CRESEMBA 200mg Powder for concentrate for solution for infusionPfizer Limited · emc · SmPC §5.2 Pharmacokinetic properties · Version 22Document updated
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